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Structure of 947249-01-6
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This boronate-functionalized pyridyl amine features a sterically shielded tetramethylboronate group paired with a trifluoromethyl substituent, enabling reliable cross-coupling under standard conditions. The electron-deficient pyridine ring enhances reactivity in palladium-catalyzed transformations, while the bench-stable boronate moiety ensures straightforward handling and integration into complex molecular architectures.
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)pyridin-2-amine serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the pyridin-2-amine scaffold provides a handle for further functionalization. Bench-stable and compatible with a broad range of reaction conditions, it facilitates efficient construction of complex heterocyclic architectures in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: