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CS-W001157 4
Total: USD 88.00

(2-Bromo-5-iodophenyl)methanol

  • CAS No. 946525-30-0

  • Cat. No. CS-0031364
  • Purity≥98%
  • MDL No.MFCD11044842
  • HazMat Fee +

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    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2-Bromo-5-iodophenyl)methanol|CS-0031364

Structure of 946525-30-0

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Description

(2-Bromo-5-iodophenyl)methanol features a dual halogenated aromatic core with bromine at the ortho position and iodine at the para position relative to the methanol group. This configuration enables selective cross-coupling reactions in transition-metal-catalyzed transformations, particularly in the synthesis of complex biaryl architectures. The benzylic alcohol functionality provides a handle for derivatization, including oxidation to aldehydes or esterification. The compound exhibits bench-stable handling under standard conditions and is compatible with palladium-catalyzed coupling protocols.

Application

(2-Bromo-5-iodophenyl)methanol serves as a versatile building block for Suzuki-Miyaura and Negishi coupling reactions, enabling the construction of biaryl scaffolds under mild conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, facilitating efficient functionalization in late-stage diversification. Its orthogonal halogen reactivity profile supports sequential cross-coupling strategies in medicinal chemistry and materials synthesis.

General Information

  • CAS No. 946525-30-0
  • Cat. No. CS-0031364
  • Purity ≥98%
  • MDL No. MFCD11044842
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrIO
  • Molecular Weight None
  • Synonym(s) 2-BROMO-5-IODOBENZYLALCOHOL
  • SMILES OCC1=CC(I)=CC=C1Br

Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.546
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H319
Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P330-P337+P313-P501

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