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Structure of 946525-30-0
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(2-Bromo-5-iodophenyl)methanol features a dual halogenated aromatic core with bromine at the ortho position and iodine at the para position relative to the methanol group. This configuration enables selective cross-coupling reactions in transition-metal-catalyzed transformations, particularly in the synthesis of complex biaryl architectures. The benzylic alcohol functionality provides a handle for derivatization, including oxidation to aldehydes or esterification. The compound exhibits bench-stable handling under standard conditions and is compatible with palladium-catalyzed coupling protocols.
(2-Bromo-5-iodophenyl)methanol serves as a versatile building block for Suzuki-Miyaura and Negishi coupling reactions, enabling the construction of biaryl scaffolds under mild conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, facilitating efficient functionalization in late-stage diversification. Its orthogonal halogen reactivity profile supports sequential cross-coupling strategies in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280-P301+P310-P305+P351+P338-P330-P337+P313-P501
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Lot numbers can be found on the outside label of a product: