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(1H-Indazol-7-yl)methanamine

  • CAS No. 944904-20-5

  • Cat. No. CS-0052542
  • Molecule weight147.18
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1H-Indazol-7-yl)methanamine|CS-0052542

Structure of 944904-20-5

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General Information

  • CAS No. 944904-20-5
  • Cat. No. CS-0052542
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉N₃
  • Molecular Weight 147.18
  • Synonym(s) 1H-Indazole-7-methanamine
  • SMILES NCC1=C2NN=CC2=CC=C1

Description

This bench-stable indazolylmethylamine features a nitrogen-rich heterocyclic core enabling direct integration into bioactive molecule scaffolds. The primary amine group facilitates conjugation reactions, while the indazole framework imparts metabolic stability and favorable binding interactions in medicinal chemistry applications.

Application

(1H-Indazol-7-yl)methanamine serves as a versatile building block for medicinal chemistry, enabling efficient access to indazole-based scaffolds through standard amine functionalization. Its primary amine functionality facilitates conjugation via amidation, alkylation, or reductive amination, while the indazole core offers enhanced metabolic stability and favorable pharmacophoric properties. The compound exhibits good bench stability and is readily purified by chromatography or recrystallization, supporting scalable synthesis in API development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   54.7
  • LogP   1.0216
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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