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CS-W001157 4
Total: USD 88.00

3-Bromo-7-azaindole

  • CAS No. 74420-15-8

  • Cat. No. CS-B0099
  • Purity≥96%
  • MDL No.MFCD02179276

*For research and further manufacturing use only, not for direct human use.

3-Bromo-7-azaindole|CS-B0099

Structure of 74420-15-8

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General Information

  • CAS No. 74420-15-8
  • Cat. No. CS-B0099
  • Purity ≥96%
  • MDL No. MFCD02179276
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅BrN₂
  • Molecular Weight 197.03
  • Synonym(s) None
  • SMILES BrC1=CNC2=C1C=CC=N2

Description

3-Bromo-7-azaindole is a heterocyclic building block featuring a brominated position at the 3-locus and a nitrogen atom at the 7-position of the indole core. This configuration imparts enhanced electronic modulation and facilitates downstream functionalization via cross-coupling reactions. The compound exhibits good stability under standard conditions and serves as a key intermediate in medicinal chemistry and materials synthesis.

Synthesis

  • Route1

    References

    • VERTEX PHARMACEUTICALS INCORPORATED; TAYLOR, Lori, Kell; SEWELL, Kathryn, Lea; HOOCK, Thomas, Carl Patent: WO2014/74471 A1, 2014 ; Location in patent: Paragraph 0268-0270 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.3254
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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