Pyrazolo[1,5-a]pyridine-7-carboxaldehyde

Name: Pyrazolo[1,5-a]pyridine-7-carboxaldehyde
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CAS No. 362661-83-4
Cat. No. CS-0132249
Purity≥97%
MDL No.MFCD06739029

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Pyrazolo[1,5-a]pyridine-7-carboxaldehyde|CS-0132249

Structure of 362661-83-4

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General Information

CAS No. 362661-83-4
Cat. No. CS-0132249
Purity ≥97%
MDL No. MFCD06739029
Storage -20°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₆N₂O
Molecular Weight 146.15
Synonym(s) Pyrazolo[1,5-a]pyridine-7-carbaldehyde
SMILES O=CC1=CC=CC2=CC=NN12

Description

Pyrazolo[1,5-a]pyridine-7-carboxaldehyde features a fused heterocyclic core with a strategically positioned aldehyde group, enabling direct functionalization in synthetic routes. The electron-deficient pyrazolo[1,5-a]pyridine scaffold enhances reactivity in nucleophilic addition and coupling processes, while the aldehyde moiety serves as a key handle for diversification via imine formation or reductive amination. This compound demonstrates stability under standard bench conditions and compatibility with common reaction media.

Application

Pyrazolo[1,5-a]pyridine-7-carboxaldehyde serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its aldehyde functionality enables direct incorporation into imine-based conjugates, Ugi-type multicomponent reactions, and reductive amination workflows. The scaffold exhibits excellent bench stability and compatibility with common protecting groups, facilitating downstream functionalization in complex molecule synthesis.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

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Computational Chemistry Data

TPSA 34.37
LogP 1.1468
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrazole compounds

Key Words

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Pyrazolo[1,5-a]pyridine-7-carboxaldehyde

CAS No. 362661-83-4

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