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CS-W001157 4
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Pyrazolo[1,5-a]pyridine-7-carboxylic acid

  • CAS No. 474432-62-7

  • Cat. No. CS-0005371
  • Purity≥98%
  • MDL No.MFCD06739030

*For research and further manufacturing use only, not for direct human use.

Pyrazolo[1,5-a]pyridine-7-carboxylic acid|CS-0005371

Structure of 474432-62-7

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General Information

  • CAS No. 474432-62-7
  • Cat. No. CS-0005371
  • Purity ≥98%
  • MDL No. MFCD06739030
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O₂
  • Molecular Weight 162.15
  • Synonym(s) Pyrazolo[1,5-a]pyridine-7-carboxylic acid (9CI)
  • SMILES O=C(O)C1=CC=CC2=CC=NN12

Description

Pyrazolo[1,5-a]pyridine-7-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 7-position, enabling direct conjugation or derivatization. This scaffold combines electron-deficient aromaticity with a polar functional handle, offering enhanced solubility and stability for use in medicinal chemistry and materials science applications.

Application

Pyrazolo[1,5-a]pyridine-7-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science. Its carboxylic acid functionality enables direct amidation, esterification, and derivatization under standard conditions. The fused pyrazolo[1,5-a]pyridine core exhibits enhanced stability and favorable electronic properties, facilitating incorporation into bioactive scaffolds and functional molecular architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   54.6
  • LogP   1.0325
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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