(1H-Indazol-5-yl)methanamine hydrochloride

Name: (1H-Indazol-5-yl)methanamine hydrochloride
Brand: ChemScene
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CAS No. 943845-78-1
Cat. No. CS-0155629
Purity≥97%
MDL No.MFCD23135684

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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(1H-Indazol-5-yl)methanamine hydrochloride|CS-0155629

Structure of 943845-78-1

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General Information

CAS No. 943845-78-1
Cat. No. CS-0155629
Purity ≥97%
MDL No. MFCD23135684
Storage Store at room temperature, keep dry and cool
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀ClN₃
Molecular Weight 183.64
Synonym(s) 1H-Indazole-5-MethanaMine Hydrochloride
SMILES NCC1=CC2=CNN=C2C=C1.Cl

Description

This bench-stable indazolylmethanamine hydrochloride features a nitrogen-rich heterocyclic core paired with a primary amine handle, enabling direct incorporation into pharmaceutical scaffolds. The protonated amine enhances solubility in aqueous systems and supports efficient salt formation for purification and formulation workflows.

Application

(1H-Indazol-5-yl)methanamine hydrochloride serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient access to indazole-based scaffolds. The primary amine functionality facilitates straightforward amidation, alkylation, and reductive amination reactions. Its crystalline solid form ensures excellent bench stability and ease of handling, while the hydrochloride salt enhances solubility in polar solvents, streamlining purification and reaction setup in standard synthetic workflows.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 54.7
LogP 1.4434
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Indazole compounds

Key Words

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(1H-Indazol-5-yl)methanamine hydrochloride

CAS No. 943845-78-1

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