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CS-W001157 4
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tert-Butyl azetidin-3-yl(methyl)carbamate (hydrochloride)-1

  • CAS No. 943060-59-1

  • Cat. No. CS-W023021
  • Purity≥97%
  • MDL No.MFCD12963843

*For research and further manufacturing use only, not for direct human use.

tert-Butyl azetidin-3-yl(methyl)carbamate (hydrochloride)-1|CS-W023021

Structure of 943060-59-1

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General Information

  • CAS No. 943060-59-1
  • Cat. No. CS-W023021
  • Purity ≥97%
  • MDL No. MFCD12963843
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₉ClN₂O₂
  • Molecular Weight 222.71
  • Synonym(s) 3-Boc-Aminomethyl Azetidine HCl
  • SMILES O=C(N(C)C1CNC1)OC(C)(C)C.Cl

Description

tert-Butyl azetidin-3-yl(methyl)carbamate hydrochloride delivers a stable, moisture-tolerant azetidine scaffold with a methyl-substituted carbamate handle. This bench-stable derivative enables efficient incorporation into bioactive molecules, offering enhanced solubility and compatibility in synthetic workflows. The protected amine facilitates straightforward deprotection under mild acidic conditions.

Application

tert-Butyl azetidin-3-yl(methyl)carbamate hydrochloride serves as a stable, bench-ready building block for the synthesis of bioactive azetidine-containing scaffolds. The protected amine enables straightforward deprotection and functionalization, while the methylcarbamate group enhances solubility and facilitates purification. Its compatibility with standard coupling reactions and tolerance to diverse functional groups make it a practical choice in medicinal chemistry workflows targeting heterocyclic drug candidates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   41.57
  • LogP   1.2469
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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