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Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

L-Homophenylalanine

  • CAS No. 943-73-7

  • Cat. No. CS-M2900
  • Purity≥98%
  • MDL No.MFCD00002619

*For research and further manufacturing use only, not for direct human use.

L-Homophenylalanine|CS-M2900

Structure of 943-73-7

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General Information

  • CAS No. 943-73-7
  • Cat. No. CS-M2900
  • Purity ≥98%
  • MDL No. MFCD00002619
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃NO₂
  • Molecular Weight 179.22
  • Synonym(s) None
  • SMILES N[C@H](C(O)=O)CCC1=CC=CC=C1

Description

L-Homophenylalanine features a phenylalanine backbone extended by a methylene group, enhancing its hydrophobic character and metabolic stability. This structural modification improves membrane permeability and resistance to enzymatic degradation, making it valuable for peptide-based drug design. The side chain’s increased lipophilicity supports integration into bioactive peptides requiring enhanced cellular uptake.

Synthesis

  • Route1
    • null|null
      139040-47-4
    • ~94%
    • In-stock
      L-Homophenylalanine|CS-M2900
      943-73-7

    References

    • Corey, E. J.; Link, John O. Journal of the American Chemical Society, 1992 , vol. 114, # 5 p. 1906 - 1908
  • Route2

    References

    • Asano; Yamada; Kato; Yamaguchi; Hibino; Hirai; Kondo Journal of Organic Chemistry, 1990 , vol. 55, # 21 p. 5567 - 5571
  • Route3
    • null|null
      100516-57-2
    • ~93%
    • In-stock
      L-Homophenylalanine|CS-M2900
      943-73-7
    • In-stock
      H-D-HoPhe-OH|CS-W017272
      82795-51-5

    References

    • Williams, Robert M.; Sinclair, Peter J.; Zhai, Dongguan; Chen, Daimo Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1547 - 1557

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   63.32
  • LogP   1.0311
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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