2-(2,5-Dimethylthiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Name: 2-(2,5-Dimethylthiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 942070-20-4
Cat. No. CS-0173882
Molecule weight238.15
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-(2,5-Dimethylthiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane|CS-0173882

Structure of 942070-20-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 942070-20-4
Cat. No. CS-0173882
Purity ≥97%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₉BO₂S
Molecular Weight 238.15
Synonym(s) 2,5-Dimethylthiophene-3-boronic acid pinacol ester
SMILES CC1=CC(B2OC(C)(C(C)(O2)C)C)=C(S1)C

Description

This boronate ester features a sterically hindered tetramethyl-1,3,2-dioxaborolane ring paired with a 2,5-dimethylthiophene moiety, delivering enhanced stability and reactivity in Suzuki-Miyaura coupling. The electron-rich thiophene unit facilitates efficient cross-coupling under mild conditions, enabling rapid access to complex arylated architectures in synthetic and medicinal chemistry workflows.

Application

2-(2,5-Dimethylthiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a stable, bench-ready boronate building block for Suzuki-Miyaura cross-coupling reactions. The thiophene core imparts enhanced electronic stability and compatibility with diverse reaction conditions, enabling efficient C–C bond formation under mild catalytic systems. Its tetramethyl-substituted dioxaborolane ring ensures high chemical stability, resistance to hydrolysis, and ease of purification, making it ideal for modular synthesis of functionalized heterocycles and complex scaffolds in medicinal chemistry and materials science applications.

Synthesis

Route1
- In-stock
  
  638-02-8
- In-stock
  
  73183-34-3
- ~99%
- In-stock
  
  942070-20-4
References
- Harrisson, Peter; Morris, James; Marder, Todd B.; Steel, Patrick G. Organic Letters, 2009 , vol. 11, # 16 p. 3586 - 3589
Route2
- In-stock
  
  638-02-8
- 25015-63-8
- ~99%
- In-stock
  
  942070-20-4
References
- Chotana, Ghayoor A.; Kallepalli, Venkata A.; Maleczka Jr., Robert E.; Smith III, Milton R. Tetrahedron, 2008 , vol. 64, # 26 p. 6103 - 6114

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 18.46
LogP 2.66414
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

942070-20-4 sigma942070-20-4 manufacturer942070-20-4 price942070-20-4 structure942070-20-4 SDSbuy 942070-20-4942070-20-4 supplier942070-20-4 uses942070-20-4 molecular weightprice of 942070-20-4942070-20-4 chemical name formula of 942070-20-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-(2,5-Dimethylthiophen-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

CAS No. 942070-20-4

Recommended Products