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CS-W001157 4
Total: USD 88.00

Ethylene Glycol Dibenzoate

  • CAS No. 94-49-5

  • Cat. No. CS-0156542
  • Purity≥98%
  • MDL No.MFCD00059685

*For research and further manufacturing use only, not for direct human use.

Ethylene Glycol Dibenzoate|CS-0156542

Structure of 94-49-5

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General Information

  • CAS No. 94-49-5
  • Cat. No. CS-0156542
  • Purity ≥98%
  • MDL No. MFCD00059685
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₄O₄
  • Molecular Weight 270.28
  • Synonym(s) Glycol Dibenzoate
  • SMILES C1=CC=C(C=C1)C(=O)OCCOC(=O)C2=CC=CC=C2

Description

Ethylene Glycol Dibenzoate serves as a stable, moisture-tolerant diester linker for conjugating aromatic moieties in synthetic workflows. This bench-stable compound features two benzoate groups flanking a central ethylene glycol backbone, enabling efficient coupling reactions under standard conditions while maintaining solubility in common organic solvents.

Application

Ethylene Glycol Dibenzoate serves as a stable, bench-ready diester reagent enabling efficient benzoylation of alcohols and amines under mild conditions. Its orthogonal functional group tolerance facilitates selective derivatization in complex molecule synthesis, while the benzoate esters are readily cleaved via hydrolysis or catalytic reduction. This compound functions as a valuable building block in the construction of heterocyclic scaffolds and provides excellent solubility and handling characteristics for industrial-scale applications.

Synthesis

  • Route1
    • null|null
      98-88-4
    • ~97%
    • In-stock
      Ethylene Glycol Dibenzoate|CS-0156542
      94-49-5

    References

    • MEDICONTUR ORVOSTECHNIKAI KFT.; NAGY, Jozsef; AGOSTON, Peter; PUSZTAI, Erika; TURKEVI-NAGY, Nandor Patent: WO2012/10918 A2, 2012 ; Location in patent: Page/Page column 10-11 ;
  • Route2
    • null|null
      106-93-4
    • null|null
      94-36-0
    • ~76%
    • In-stock
      Ethylene Glycol Dibenzoate|CS-0156542
      94-49-5

    References

    • Chen, Huan-Huan; Wang, Guang-Zu; Han, Jin; Xu, Meng-Yu; Zhao, Yong-Qiang; Xu, Hua-Jian Tetrahedron, 2014 , vol. 70, # 2 p. 212 - 217
  • Route3
    • null|null
      4344-45-0
    • ~99%
    • In-stock
      Ethylene Glycol Dibenzoate|CS-0156542
      94-49-5

    References

    • Tamagaki, Seizo; Liesner, Cathy E.; Neckers, Douglas C. Journal of Organic Chemistry, 1980 , vol. 45, # 9 p. 1573 - 1576

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08,GHS09
Signal Word : Danger
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H302-H361-H372-H410
Precautionary Statements : P260-P264-P270-P273-P280-P330-P391-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   52.6
  • LogP   2.7004
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   5

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