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(R)-4-Isopropyl-2-(quinolin-2-yl)-4,5-dihydrooxazole

  • CAS No. 933992-49-5

  • Cat. No. CS-0104436
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-4-Isopropyl-2-(quinolin-2-yl)-4,5-dihydrooxazole|CS-0104436

Structure of 933992-49-5

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General Information

  • CAS No. 933992-49-5
  • Cat. No. CS-0104436
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₆N₂O
  • Molecular Weight 240.30
  • Synonym(s) (R)-4-Isopropyl-2-(quinolin-2-yl)-4,5-dihydrooxazole
  • SMILES CC([C@@H]1COC(C2=NC3=CC=CC=C3C=C2)=N1)C

Description

(R)-iPr-Quinox delivers a chiral, bench-stable quinoxaline scaffold with enhanced solubility and compatibility in asymmetric synthesis. This sterically defined heteroaromatic moiety integrates seamlessly into complex molecular architectures, enabling efficient access to bioactive scaffolds under standard conditions.

Application

(R)-iPr-Quinox serves as a chiral auxiliary in asymmetric synthesis, enabling stereoselective construction of quinoline and quinoxaline scaffolds. Its isopropyl-substituted backbone enhances bench stability and facilitates straightforward purification. The configurationally stable chiral center promotes high diastereoselectivity in electrophilic substitution and cycloaddition reactions, making it a reliable choice for medicinal chemistry campaigns requiring controlled stereochemistry.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   34.48
  • LogP   3.0362
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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