Lot numbers can be found on the outside label of a product:
2-(Quinolin-2-yl)-4,5-dihydrooxazole
-
CAS No. 202191-12-6
- Cat. No. CS-0094592
- Purity≥97%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 202191-12-6
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 202191-12-6
- Cat. No. CS-0094592
- Purity ≥97%
- MDL No. None
- Storage -20°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₂H₁₀N₂O
- Molecular Weight 198.22
- Synonym(s) 2-(4,5-Dihydro-2-oxazolyl)quinoline
- SMILES C1(C2=NC3=CC=CC=C3C=C2)=NCCO1
Description
This oxazole scaffold integrates a quinolin-2-yl moiety, delivering enhanced π-conjugation and improved solubility in polar organic solvents. The dihydrooxazole ring exhibits stability under standard bench conditions and facilitates efficient coupling reactions in synthetic pathways targeting bioactive heterocycles.
Application
2-(Quinolin-2-yl)-4,5-dihydrooxazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to quinoline-fused oxazoles via standard functionalization protocols. Its bench-stable nature and compatibility with common coupling reactions facilitate integration into complex molecular architectures. The dihydrooxazole core provides a rigid, polar scaffold with moderate lipophilicity, supporting diverse downstream transformations including oxidation, reduction, and metal-catalyzed cross-couplings.
Synthesis
-
Route1
-
100142-77-6 - ~71%
-
In-stock
202191-12-6
References
-
Sigman, Matthew Scott; Michel, Brian William Patent: US2011/54176 A1, 2011 ; Location in patent: Page/Page column 7-8 ;
-
-
Route2
-
202191-13-7
- ~%
-
In-stock
202191-12-6
References
-
Michel, Brian W.; McCombs, Jessica R.; Winkler, Andrea; Sigman, Matthew S. Angewandte Chemie - International Edition, 2010 , vol. 49, # 40 p. 7312 - 7315
-
-
Route3
-
In-stock
93-10-7 - ~%
-
In-stock
202191-12-6
References
-
Sigman, Matthew Scott; Michel, Brian William Patent: US2011/54176 A1, 2011 ;
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H315-H319
|
|
|
Precautionary Statements : P264-P280-P302+P352
|
|
Quality Control
Computational Chemistry Data
- TPSA 34.48
- LogP 2.0116
- H_Acceptors 3
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2-(Quinolin-2-yl)-4,5-dihydrooxazole sigma2-(Quinolin-2-yl)-4,5-dihydrooxazole manufacturer2-(Quinolin-2-yl)-4,5-dihydrooxazole price2-(Quinolin-2-yl)-4,5-dihydrooxazole structure2-(Quinolin-2-yl)-4,5-dihydrooxazole SDSbuy 2-(Quinolin-2-yl)-4,5-dihydrooxazole2-(Quinolin-2-yl)-4,5-dihydrooxazole supplier2-(Quinolin-2-yl)-4,5-dihydrooxazole uses2-(Quinolin-2-yl)-4,5-dihydrooxazole molecular weightprice of 2-(Quinolin-2-yl)-4,5-dihydrooxazole2-(Quinolin-2-yl)-4,5-dihydrooxazole chemical name formula of 2-(Quinolin-2-yl)-4,5-dihydrooxazole