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CS-W001157 4
Total: USD 88.00

1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid

  • CAS No. 932702-11-9

  • Cat. No. CS-W006035
  • Molecule weight163.13
  • Purity≥98%
  • MDL No.MFCD11042720

*For research and further manufacturing use only, not for direct human use.

1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid|CS-W006035

Structure of 932702-11-9

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General Information

  • CAS No. 932702-11-9
  • Cat. No. CS-W006035
  • Purity ≥98%
  • MDL No. MFCD11042720
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O₂
  • Molecular Weight 163.13
  • Synonym(s) 1H-Pyrazolo[4,3-c]pyridine-3-carboxylicacid
  • SMILES [NH]1C2=C(C(=N1)C(=O)O)C=NC=C2

Description

1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid features a fused heterocyclic core combining pyrazole and pyridine moieties, delivering enhanced electron delocalization and structural rigidity. This scaffold integrates readily into bioactive molecules, offering high metabolic stability and favorable solubility profiles for medicinal chemistry applications.

Application

1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its fused tricyclic core provides enhanced rigidity and π-conjugation, enabling efficient incorporation into bioactive scaffolds. The carboxylic acid functionality facilitates direct derivatization via amide coupling, esterification, or metal complexation, supporting diverse downstream transformations. Bench-stable and compatible with standard synthetic protocols, it functions effectively in both solution-phase and solid-phase synthesis workflows.

Synthesis

  • Route1
    • null|null
      932702-12-0
    • ~45%
    • In-stock
      1H-Pyrazolo[4,3-c]pyridine-3-carboxylic acid|CS-W006035
      932702-11-9
    • null|null
      936923-48-7

    References

    • US2007/78147 A1, ; Page/Page column 69 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.6561
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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