2-Chloro-1,7-naphthyridin-8(7H)-one

Name: 2-Chloro-1,7-naphthyridin-8(7H)-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 930303-55-2
Cat. No. CS-0134053
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2-Chloro-1,7-naphthyridin-8(7H)-one|CS-0134053

Structure of 930303-55-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 930303-55-2
Cat. No. CS-0134053
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅ClN₂O
Molecular Weight 180.59
Synonym(s) 2-chloro-7H-1,7-naphthyridin-8-one
SMILES O=C1NC=CC2=C1N=C(C=C2)Cl

Description

2-Chloro-1,7-naphthyridin-8(7H)-one features a chlorine-substituted naphthyridinone core with enhanced electron-deficiency, enabling efficient coupling in transition-metal-catalyzed reactions. This bench-stable scaffold integrates readily into pharmaceutical intermediates and functional materials, offering robust reactivity under standard conditions.

Application

2-Chloro-1,7-naphthyridin-8(7H)-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of nitrogen-containing heterocycles. Its chloro group facilitates nucleophilic substitution reactions, while the quinoline-like scaffold offers favorable π-stacking and hydrogen-bonding interactions in target binding. The compound exhibits good bench stability and compatibility with standard coupling protocols, making it suitable for rapid diversification in lead optimization campaigns.

Synthesis

Route1
- 930303-54-1
- ~57%
- In-stock
  
  930303-55-2
References
- Jaeschke, Georg; Kolczewski, Sabine; Porter, Richard Hugh Philip; Schnider, Patrick; Vieira, Eric Patent: US2007/78155 A1, 2007 ; Location in patent: Page/Page column 30 ; US 20070078155 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 45.75
LogP 1.5765
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

2-Chloro-1,7-naphthyridin-8(7H)-one sigma2-Chloro-1,7-naphthyridin-8(7H)-one manufacturer2-Chloro-1,7-naphthyridin-8(7H)-one price2-Chloro-1,7-naphthyridin-8(7H)-one structure2-Chloro-1,7-naphthyridin-8(7H)-one SDSbuy 2-Chloro-1,7-naphthyridin-8(7H)-one2-Chloro-1,7-naphthyridin-8(7H)-one supplier2-Chloro-1,7-naphthyridin-8(7H)-one uses2-Chloro-1,7-naphthyridin-8(7H)-one molecular weightprice of 2-Chloro-1,7-naphthyridin-8(7H)-one2-Chloro-1,7-naphthyridin-8(7H)-one chemical name formula of 2-Chloro-1,7-naphthyridin-8(7H)-one

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-1,7-naphthyridin-8(7H)-one

CAS No. 930303-55-2

Recommended Products