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Structure of 41051-15-4
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Methyl 4-methoxyacetoacetate has been used in generation of a small focused library of diversely functionalized dihydropyrimidine derivatives via one-pot three-component Biginelli cyclocondensation of -ketoesters, aldehydes and (thio)ureas.
Methyl 4-methoxy-3-oxobutanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted γ-keto esters and heterocyclic scaffolds. Its α,β-unsaturated carbonyl system facilitates Michael additions and Claisen condensations, while the methyl ester and methoxy group provide orthogonal reactivity for downstream functionalization. Bench-stable and readily purified by distillation or chromatography, it functions reliably in multi-step syntheses requiring controlled electrophilic activation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: