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Structure of 929971-93-7
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tert-Butyl 8-hydroxy-5-azaspiro[3.5]nonane-5-carboxylate features a spirocyclic scaffold with a hydroxyl group at C8 and a nitrogen atom at the bridgehead position, delivering enhanced rigidity and stereochemical control. This configuration enables selective functionalization in complex molecule synthesis. The tert-butyl ester serves as a stable, easily removable protecting group under mild acidic conditions. The compound exhibits excellent bench stability and solubility in common organic solvents, facilitating its use in iterative synthetic sequences.
tert-Butyl 8-hydroxy-5-azaspiro[3.5]nonane-5-carboxylate serves as a versatile spirocyclic building block for medicinal chemistry and process development. The hydroxyl group enables facile derivatization via esterification, etherification, or oxidation, while the protected amine and spirocyclic scaffold provide rigidity and defined stereochemistry. Its bench-stable tert-butyl carbamate functionality facilitates selective deprotection under mild acidic conditions, supporting efficient route optimization in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: