(R)-2-Amino-2-(3-chlorophenyl)ethanol

Name: (R)-2-Amino-2-(3-chlorophenyl)ethanol
Brand: ChemScene
Availability: InStock
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CAS No. 926291-77-2
Cat. No. CS-W020717
Purity≥97%
MDL No.MFCD06659478

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-2-Amino-2-(3-chlorophenyl)ethanol|CS-W020717

Structure of 926291-77-2

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General Information

CAS No. 926291-77-2
Cat. No. CS-W020717
Purity ≥97%
MDL No. MFCD06659478
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀ClNO
Molecular Weight 171.62
Synonym(s) (R)-3-Chlorophenylglycinol
SMILES ClC1=CC([C@H](CO)N)=CC=C1

Description

(R)-2-Amino-2-(3-chlorophenyl)ethanol is a chiral building block featuring a stereogenic center and a para-chlorinated aromatic ring. This bench-stable amino alcohol integrates readily into asymmetric synthesis, offering high enantioselectivity in catalytic transformations. Its electron-deficient phenyl moiety enhances reactivity in transition-metal-catalyzed couplings.

Application

(R)-2-Amino-2-(3-chlorophenyl)ethanol serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established amino-alcohol transformations. Its bench-stable nature and defined stereochemistry facilitate reliable incorporation into pharmaceutical intermediates, particularly in the construction of β-amino alcohol motifs found in CNS-targeted therapeutics and enzyme inhibitors.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 46.25
LogP 1.3321
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Functional Group Chloride

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(R)-2-Amino-2-(3-chlorophenyl)ethanol

CAS No. 926291-77-2

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