Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Trifluoromethyl)thiazole-5-carboxylic acid

  • CAS No. 1286734-84-6

  • Cat. No. CS-W007256
  • Purity≥98%
  • MDL No.MFCD18632534

*For research and further manufacturing use only, not for direct human use.

2-(Trifluoromethyl)thiazole-5-carboxylic acid|CS-W007256

Structure of 1286734-84-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1286734-84-6
  • Cat. No. CS-W007256
  • Purity ≥98%
  • MDL No. MFCD18632534
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂F₃NO₂S
  • Molecular Weight 197.14
  • Synonym(s) 2-(Trifluoromethyl)-1,3-thiazole-5-carboxylic acid
  • SMILES O=C(C1=CN=C(C(F)(F)F)S1)O

Description

2-(Trifluoromethyl)thiazole-5-carboxylic acid features a trifluoromethyl group at the 2-position and a carboxylic acid at the 5-position of the thiazole ring, conferring strong electron-withdrawing character and enhanced metabolic stability. This scaffold integrates readily into bioactive molecules, particularly in medicinal chemistry applications targeting kinase inhibition and antimicrobial agents. The compound exhibits excellent solubility in polar aprotic solvents and maintains stability under standard bench conditions.

Application

2-(Trifluoromethyl)thiazole-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates direct derivatization or incorporation into peptide-like scaffolds. The molecule exhibits excellent bench stability and compatibility with common reaction conditions, making it ideal for iterative synthesis campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.8601
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1286734-84-6 sigma1286734-84-6 manufacturer1286734-84-6 price1286734-84-6 structure1286734-84-6 SDSbuy 1286734-84-61286734-84-6 supplier1286734-84-6 uses1286734-84-6 molecular weightprice of 1286734-84-61286734-84-6 chemical name formula of 1286734-84-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label