H-D-Phg-OtBu

Name: H-D-Phg-OtBu
Brand: ChemScene
Availability: InStock
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CAS No. 65715-93-7
Cat. No. CS-W022749
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 65715-93-7
Cat. No. CS-W022749
Purity ≥98%
MDL No. None
Storage -20°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₁₇NO₂
Molecular Weight 207.27
Synonym(s) H-D-PHG-OTBU HCL
SMILES O=C(OC(C)(C)C)[C@H](N)C1=CC=CC=C1

Description

H-D-Phg-OtBu is a bench-stable, moisture-tolerant dipeptide building block featuring a protected aspartic acid residue and a phenylglycine moiety. This orthogonal handle enables direct incorporation into peptide chains under standard coupling conditions, streamlining synthesis of bioactive sequences without side-reaction complications.

Application

H-D-Phg-OtBu serves as a stable, bench-ready building block for peptide synthesis, enabling efficient incorporation of D-phenylglycine units into bioactive sequences. Its tert-butyl ester group provides excellent functional group tolerance and simplifies purification, while the D-stereochemistry offers predictable conformational control in cyclic peptides and peptidomimetics.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 52.32
LogP 2.0281
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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H-D-Phg-OtBu

CAS No. 65715-93-7

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