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CS-W001157 4
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(R)-3-Methylpiperazin-2-one

  • CAS No. 922178-61-8

  • Cat. No. CS-0042202
  • Purity≥98%
  • MDL No.MFCD07373460

*For research and further manufacturing use only, not for direct human use.

(R)-3-Methylpiperazin-2-one|CS-0042202

Structure of 922178-61-8

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General Information

  • CAS No. 922178-61-8
  • Cat. No. CS-0042202
  • Purity ≥98%
  • MDL No. MFCD07373460
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₀N₂O
  • Molecular Weight 114.15
  • Synonym(s) (R)-3-METHYL-2-KETOPIPERAZINE
  • SMILES O=C1NCCN[C@@H]1C

Description

(R)-3-Methylpiperazin-2-one is a chiral heterocyclic scaffold featuring a stereodefined methyl group at the 3-position, enhancing its rigidity and distinct binding profile. This bench-stable ketone integrates readily into medicinal chemistry libraries, offering a polar, nitrogen-rich core for targeted ligand design.

Application

(R)-3-Methylpiperazin-2-one serves as a versatile chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard amine functionalization and cyclization protocols. Its stability under routine reaction conditions, combined with predictable stereochemistry and compatibility with diverse coupling reactions, facilitates efficient synthesis of complex scaffolds for drug discovery applications.

Safety Information

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GHS Pictogram :
GHS No : GHS08
Signal Word : Danger
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319-H334
Precautionary Statements : P261-P264-P280-P285-P501

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Computational Chemistry Data

  • TPSA   41.13
  • LogP   -0.9057
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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