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CS-W001157 4
Total: USD 88.00

5-Chloropyridazin-3(2H)-one

  • CAS No. 660425-07-0

  • Cat. No. CS-W003825
  • Purity≥97%
  • MDL No.MFCD12198134

*For research and further manufacturing use only, not for direct human use.

5-Chloropyridazin-3(2H)-one|CS-W003825

Structure of 660425-07-0

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General Information

  • CAS No. 660425-07-0
  • Cat. No. CS-W003825
  • Purity ≥97%
  • MDL No. MFCD12198134
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃ClN₂O
  • Molecular Weight 130.53
  • Synonym(s) None
  • SMILES O=C1C=C(Cl)C=NN1

Description

5-Chloropyridazin-3(2H)-one is a bench-stable heterocyclic compound featuring a chlorine atom at the 5-position and a lactam functionality at the 3-position. This electron-deficient core integrates readily into synthetic scaffolds for medicinal chemistry, offering enhanced solubility and stability in aqueous environments.

Application

5-Chloropyridazin-3(2H)-one serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridazinone-based scaffolds. Its chlorine substituent facilitates nucleophilic displacement reactions, supporting the introduction of diverse amine and heterocyclic side chains. The compound exhibits good bench stability and is compatible with standard purification methods, making it well-suited for iterative synthesis campaigns in API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   0.4233
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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