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CS-W001157 4
Total: USD 88.00

(3-Methoxy-4-methylphenyl)boronic acid

  • CAS No. 917757-15-4

  • Cat. No. CS-W016069
  • Purity≥97%
  • MDL No.MFCD08274479

*For research and further manufacturing use only, not for direct human use.

(3-Methoxy-4-methylphenyl)boronic acid|CS-W016069

Structure of 917757-15-4

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General Information

  • CAS No. 917757-15-4
  • Cat. No. CS-W016069
  • Purity ≥97%
  • MDL No. MFCD08274479
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₃
  • Molecular Weight 165.98
  • Synonym(s) boronic acid, B-(3-methoxy-4-methylphenyl)-
  • SMILES OB(C1=CC=C(C)C(OC)=C1)O

Description

This boronic acid features a methoxy-substituted aromatic ring paired with a methyl group at the para position, enabling efficient coupling in Suzuki-Miyaura reactions. The electron-donating methoxy moiety enhances reactivity while maintaining bench-stable handling characteristics under standard conditions.

Application

(3-Methoxy-4-methylphenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its ortho-substituted aryl boronic acid structure provides enhanced stability and predictable reactivity, with good functional group tolerance and ease of purification. The methoxy and methyl groups offer complementary electronic and steric modulation, facilitating access to complex aromatic scaffolds relevant in medicinal chemistry and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   49.69
  • LogP   -0.31658
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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