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CS-W001157 4
Total: USD 88.00

3-(Ethylsulfonyl)phenylboronic acid

  • CAS No. 845870-47-5

  • Cat. No. CS-0007635
  • Purity≥95%
  • MDL No.MFCD03095257

*For research and further manufacturing use only, not for direct human use.

3-(Ethylsulfonyl)phenylboronic acid|CS-0007635

Structure of 845870-47-5

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General Information

  • CAS No. 845870-47-5
  • Cat. No. CS-0007635
  • Purity ≥95%
  • MDL No. MFCD03095257
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₄S
  • Molecular Weight 214.05
  • Synonym(s) 3-Ethylsulfonylphenylboronic acid
  • SMILES O=S(C1=CC(B(O)O)=CC=C1)(CC)=O

Description

3-(Ethylsulfonyl)phenylboronic acid delivers a robust boronate handle flanked by an electron-withdrawing ethylsulfonyl group, enhancing stability and tuning reactivity in Suzuki-Miyaura coupling. This bench-stable reagent integrates readily into complex molecule synthesis under standard conditions.

Application

3-(Ethylsulfonyl)phenylboronic acid serves as a robust building block for Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds with enhanced solubility and metabolic stability. The ethylsulfonyl group confers excellent bench stability, mild functional group tolerance, and facilitates purification via standard chromatographic methods. Its compatibility with diverse reaction conditions makes it a practical choice for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   -0.84
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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