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CS-W001157 4
Total: USD 88.00

3-(Methylsulfonyl)phenylboronic acid

  • CAS No. 373384-18-0

  • Cat. No. CS-D1042
  • Purity≥98%
  • MDL No.MFCD03092935

*For research and further manufacturing use only, not for direct human use.

3-(Methylsulfonyl)phenylboronic acid|CS-D1042

Structure of 373384-18-0

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General Information

  • CAS No. 373384-18-0
  • Cat. No. CS-D1042
  • Purity ≥98%
  • MDL No. MFCD03092935
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉BO₄S
  • Molecular Weight 200.02
  • Synonym(s) 3-(Methanesulfonyl)phenyl boronic acid
  • SMILES O=S(C1=CC(B(O)O)=CC=C1)(C)=O

Description

3-(Methylsulfonyl)phenylboronic acid delivers a robust boronate handle with enhanced solubility and stability, enabling efficient Suzuki-Miyaura coupling under standard conditions. The electron-withdrawing methylsulfonyl group modulates reactivity while maintaining compatibility with diverse functional groups.

Application

3-(Methylsulfonyl)phenylboronic acid serves as a robust building block for Suzuki-Miyaura cross-coupling reactions, offering excellent stability and compatibility with diverse functional groups. Its methylsulfonyl moiety enhances solubility and modulates electronic properties, enabling efficient late-stage functionalization in complex molecule synthesis. The compound facilitates reliable C–C bond formation under standard catalytic conditions, making it a practical choice for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   -1.2301
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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