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CS-W001157 4
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(2-(Methylsulfonyl)phenyl)boronic acid

  • CAS No. 330804-03-0

  • Cat. No. CS-0150151
  • Purity≥97%
  • MDL No.MFCD02179472

*For research and further manufacturing use only, not for direct human use.

(2-(Methylsulfonyl)phenyl)boronic acid|CS-0150151

Structure of 330804-03-0

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General Information

  • CAS No. 330804-03-0
  • Cat. No. CS-0150151
  • Purity ≥97%
  • MDL No. MFCD02179472
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉BO₄S
  • Molecular Weight 200.02
  • Synonym(s) 3-(Methanesulphonyl)phenylboronic acid
  • SMILES CS(=O)(=O)C1=C(C=CC=C1)B(O)O

Description

This boronic acid features a methylsulfonyl group at the ortho position, enhancing solubility and metabolic stability. The aryl boronic moiety enables efficient Suzuki-Miyaura cross-coupling under standard conditions, delivering robust yields in the synthesis of biaryl scaffolds for pharmaceutical development.

Application

(2-(Methylsulfonyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. The methylsulfonyl group enhances solubility and stability while maintaining compatibility with diverse functional groups, facilitating straightforward purification and broad applicability in the synthesis of biaryl scaffolds for pharmaceutical and agrochemical research.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   74.6
  • LogP   -1.2301
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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