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Structure of 915030-08-9
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2-(Trifluoromethyl)thiazole-4-carboxylic acid features a trifluoromethyl group at the 2-position and a carboxylic acid at the 4-position on a thiazole scaffold, delivering enhanced electron-withdrawing character and metabolic stability. This configuration supports direct incorporation into bioactive molecules, particularly in medicinal chemistry campaigns targeting kinase inhibitors and antimicrobial agents. The compound exhibits good solubility under standard conditions and maintains bench stability during routine handling.
2-(Trifluoromethyl)thiazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and functionalization reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the carboxylic acid facilitates direct amide formation or derivatization. The molecule exhibits good bench stability and compatibility with common reaction conditions, making it ideal for iterative library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: