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CS-W001157 4
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2-(3-Bromophenyl)cyclopropane-1-carboxylic acid

  • CAS No. 91445-84-0

  • Cat. No. CS-0030158
  • Molecule weight241.08
  • Purity≥95%
  • MDL No.MFCD11895900

*For research and further manufacturing use only, not for direct human use.

2-(3-Bromophenyl)cyclopropane-1-carboxylic acid|CS-0030158

Structure of 91445-84-0

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General Information

  • CAS No. 91445-84-0
  • Cat. No. CS-0030158
  • Purity ≥95%
  • MDL No. MFCD11895900
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉BrO₂
  • Molecular Weight 241.08
  • Synonym(s) 2-(3-Bromophenyl)cyclopropanecarboxylic acid
  • SMILES O=C(C1C(C2=CC=CC(Br)=C2)C1)O

Description

This cyclopropane carboxylic acid features a brominated phenyl substituent at the 3-position, delivering a rigid, electron-deficient aromatic handle. The strained cyclopropyl ring enhances reactivity in transition metal-catalyzed couplings, while the carboxylic acid group enables direct derivatization. Ideal for constructing complex heterocycles and bioactive scaffolds in medicinal chemistry.

Application

2-(3-Bromophenyl)cyclopropane-1-carboxylic acid serves as a versatile building block for medicinal chemistry and catalytic synthesis, enabling direct incorporation of a brominated aromatic moiety into cyclopropyl frameworks. Its stability under standard reaction conditions and compatibility with palladium-catalyzed cross-coupling reactions facilitate efficient diversification. The carboxylic acid group provides a handle for derivatization, including amide formation or esterification, supporting modular synthesis of bioactive scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.6372
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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