Fmoc-Arg-OH

Name: Fmoc-Arg-OH
Brand: ChemScene
Availability: InStock
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CAS No. 91000-69-0
Cat. No. CS-W014466
Purity≥98%
MDL No.MFCD00051770

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 91000-69-0

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General Information

CAS No. 91000-69-0
Cat. No. CS-W014466
Purity ≥98%
MDL No. MFCD00051770
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₂₄N₄O₄
Molecular Weight 396.44
Synonym(s) Fmoc-L-Arginine
SMILES NC(NCCC[C@@H](C(O)=O)NC(OCC1C2=CC=CC=C2C3=C1C=CC=C3)=O)=N

Description

Fmoc-Arg-OH is a bench-stable, moisture-tolerant amino acid derivative featuring a protected guanidino side chain. This reagent integrates seamlessly into solid-phase peptide synthesis workflows, enabling efficient incorporation of arginine residues with high fidelity and minimal epimerization.

Application

Fmoc-Arg-OH serves as a cornerstone building block in solid-phase peptide synthesis, enabling efficient incorporation of arginine residues with high fidelity. The Fmoc group provides orthogonal protection compatible with standard deprotection protocols, while the guanidino side chain offers robust functionality for downstream conjugation and bioactive peptide assembly. Bench-stable and readily purified by recrystallization or chromatography, it supports scalable synthesis of complex peptides and peptidomimetics.

Synthesis

Route1
- 74-79-3
- In-stock
  
  82911-69-1
- ~55%
- In-stock
  
  91000-69-0
References
- Nowshuddin, Shaik; Rao; Reddy, A. Ram Synthetic Communications, 2009 , vol. 39, # 11 p. 2022 - 2031
Route2
- 74-79-3
- 28920-43-6
- ~%
- In-stock
  
  91000-69-0
References
- Journal of the Chinese Chemical Society, , vol. 58, # 4 p. 509 - 515
Route3
- 1202179-48-3
- ~12%
- 1202179-54-1
- In-stock
  
  91000-69-0
References
- Synthesis, , # 20 p. 3460 - 3466

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 137.53
LogP 2.24157
H_Acceptors 4
H_Donors 5
Rotatable_Bonds 8

Other Classifications

Life Science Amino Acids and their Derivatives Arginine and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Fmoc-Arg-OH

CAS No. 91000-69-0

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