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Structure of 90874-41-2
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3-Phenylcyclobutan-1-amine features a rigid cyclobutane scaffold bearing a primary amine and a phenyl substituent, enabling precise spatial orientation in molecular design. This structural motif delivers enhanced metabolic stability and favorable lipophilicity profiles, making it a valuable scaffold for medicinal chemistry campaigns targeting CNS-penetrant therapeutics and bioactive heterocycles.
3-Phenylcyclobutan-1-amine serves as a valuable scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard functionalization. Its rigid cyclobutane core provides conformational constraint, while the primary amine facilitates derivatization via alkylation, acylation, or coupling reactions. The compound exhibits good bench stability and is compatible with common protecting group strategies, making it suitable for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: