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Structure of 1807916-62-6
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cis-3-Phenylcyclobutan-1-amine hydrochloride features a rigid, conformationally constrained cyclobutane core with a phenyl group in the cis orientation relative to the amine. This stereochemistry imparts distinct spatial presentation of the aromatic ring and nitrogen functionality, enhancing its utility as a chiral building block in medicinal chemistry. The hydrochloride salt ensures improved solubility and stability under standard bench conditions, facilitating straightforward handling in synthetic workflows.
cis-3-Phenylcyclobutan-1-amine hydrochloride serves as a valuable chiral building block for medicinal chemistry and asymmetric synthesis. The cis-configured cyclobutane scaffold provides rigidity and defined stereochemistry, enabling precise spatial orientation in target molecules. The amine functionality facilitates straightforward derivatization via acylation, alkylation, or reductive amination, while the hydrochloride salt enhances solubility and stability for handling. This compound is well-suited for constructing bioactive heterocycles and peptide mimetics requiring constrained scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: