Lot numbers can be found on the outside label of a product:
7-Chloro-1,2,3,4-tetrahydroquinoline
-
CAS No. 90562-35-9
- Cat. No. CS-0040537
- Purity≥97%
- MDL No.MFCD08544268
*For research and further manufacturing use only, not for direct human use.
Structure of 90562-35-9
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 90562-35-9
- Cat. No. CS-0040537
- Purity ≥97%
- MDL No. MFCD08544268
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₉H₁₀ClN
- Molecular Weight 167.64
- Synonym(s) 7-chloro-tetrahydroquinoline
- SMILES ClC1=CC2=C(C=C1)CCCN2
Description
7-Chloro-1,2,3,4-tetrahydroquinoline is a bench-stable heterocyclic scaffold featuring a chlorinated aromatic ring fused to a saturated nitrogen-containing system. This electron-deficient core integrates readily into medicinal chemistry libraries, offering enhanced metabolic stability and improved membrane permeability in bioactive molecule design.
Application
7-Chloro-1,2,3,4-tetrahydroquinoline serves as a versatile heterocyclic building block in medicinal chemistry, offering a stable, electron-deficient scaffold for late-stage functionalization. Its chlorinated aromatic ring enables palladium-catalyzed cross-coupling reactions, while the saturated nitrogen facilitates salt formation and solubility optimization. The compound exhibits excellent bench stability and compatibility with common protecting group strategies, enabling efficient incorporation into complex molecular architectures.
Synthesis
-
Route1
-
In-stock
612-61-3 - ~71%
-
In-stock
90562-35-9
References
-
Al-Awar, Rima Salim; Hecker, Kyle Andrew; Ray, James Edward; Huang, Jianping; Joseph, Sajan; Li, Tiechao; Paal, Michael; Rathnachalam, Radhakrishnan; Shih, Chuan; Waid, Philip Parker; Zhou, Xun; Zhu, Guoxin Patent: US2003/229026 A1, 2003 ; Location in patent: Page 25 ; US 20030229026 A1
-
-
Route2
-
In-stock
86-98-6 - ~%
-
In-stock
90562-35-9
References
-
Buchanan, John L.; Kim, Joseph L.; Novak, Perry M.; Nunes, Joseph J.; Patel, Vinod F. Patent: US2003/139416 A1, 2003 ;
-
-
Route3
-
98591-57-2 - ~19%
-
In-stock
612-61-3
-
In-stock
90562-35-9
References
-
Sugimoto, Osamu; Sugiyama, Minami; Tanji, Ken-ichi Heterocycles, 2010 , vol. 80, # 1 p. 601 - 606
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 12.03
- LogP 2.6981
- H_Acceptors 1
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 7-Chloro-1,2,3,4-tetrahydroquinoline sigma7-Chloro-1,2,3,4-tetrahydroquinoline manufacturer7-Chloro-1,2,3,4-tetrahydroquinoline price7-Chloro-1,2,3,4-tetrahydroquinoline structure7-Chloro-1,2,3,4-tetrahydroquinoline SDSbuy 7-Chloro-1,2,3,4-tetrahydroquinoline7-Chloro-1,2,3,4-tetrahydroquinoline supplier7-Chloro-1,2,3,4-tetrahydroquinoline uses7-Chloro-1,2,3,4-tetrahydroquinoline molecular weightprice of 7-Chloro-1,2,3,4-tetrahydroquinoline7-Chloro-1,2,3,4-tetrahydroquinoline chemical name formula of 7-Chloro-1,2,3,4-tetrahydroquinoline