Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1,2,3,4-Tetrahydroquinaldine

  • CAS No. 1780-19-4

  • Cat. No. CS-W019554
  • Purity≥98%
  • MDL No.MFCD00023886

*For research and further manufacturing use only, not for direct human use.

1,2,3,4-Tetrahydroquinaldine|CS-W019554

Structure of 1780-19-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1780-19-4
  • Cat. No. CS-W019554
  • Purity ≥98%
  • MDL No. MFCD00023886
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₃N
  • Molecular Weight None
  • Synonym(s) Quinoline, 1,2,3,4-tetrahydro-2-methyl- (9CI)
  • SMILES CC1CCC2=CC=CC=C2N1

Description

1,2,3,4-Tetrahydroquinaldine features a saturated quinoline core with enhanced solubility and reduced aromaticity, enabling efficient integration into catalytic systems. This bench-stable heterocycle serves as a key scaffold in medicinal chemistry, where its nitrogen-rich framework supports hydrogen bonding and metal coordination.

Application

1,2,3,4-Tetrahydroquinaldine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to quinoline-based scaffolds through standard functionalization protocols. Its saturated ring system offers enhanced stability and solubility compared to aromatic analogs, facilitating purification and handling. The molecule functions effectively as a nitrogen-containing synthon in transition-metal-catalyzed couplings and reductive amination reactions, supporting the construction of complex alkaloid frameworks and drug-like intermediates with predictable reactivity.

Synthesis

  • Route1
    • null|null
      91-63-4
    • ~98%
    • In-stock
      1,2,3,4-Tetrahydroquinaldine|CS-W019554
      1780-19-4

    References

    • Wu, Jianjun; Barnard, Jonathan H.; Zhang, Yi; Talwar, Dinesh; Robertson, Craig M.; Xiao, Jianliang Chemical Communications, 2013 , vol. 49, # 63 p. 7052 - 7054
  • Route2
    • null|null
      20766-40-9
    • ~91%
    • In-stock
      1,2,3,4-Tetrahydroquinaldine|CS-W019554
      1780-19-4

    References

    • Patti, Angela; Pedotti, Sonia Tetrahedron, 2010 , vol. 66, # 30 p. 5607 - 5611
  • Route3
    • null|null
      457622-20-7
    • ~83%
    • null|null
      91-63-4
    • In-stock
      1,2,3,4-Tetrahydroquinaldine|CS-W019554
      1780-19-4

    References

    • Organic Letters, , vol. 4, # 16 p. 2691 - 2694

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   12.03
  • LogP   2.4332
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1,2,3,4-Tetrahydroquinaldine sigma1,2,3,4-Tetrahydroquinaldine manufacturer1,2,3,4-Tetrahydroquinaldine price1,2,3,4-Tetrahydroquinaldine structure1,2,3,4-Tetrahydroquinaldine SDSbuy 1,2,3,4-Tetrahydroquinaldine1,2,3,4-Tetrahydroquinaldine supplier1,2,3,4-Tetrahydroquinaldine uses1,2,3,4-Tetrahydroquinaldine molecular weightprice of 1,2,3,4-Tetrahydroquinaldine1,2,3,4-Tetrahydroquinaldine chemical name formula of 1,2,3,4-Tetrahydroquinaldine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label