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Structure of 91-61-2
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6-Methyl-1,2,3,4-tetrahydroquinoline is a bench-stable, electron-rich heterocycle featuring a saturated quinoline core with a methyl group at the 6-position. This substitution enhances regioselectivity in coupling reactions and improves solubility in organic media. The compound serves as a key scaffold in medicinal chemistry for targeted ligand design and bioactive molecule synthesis.
6-Methyl-1,2,3,4-tetrahydroquinoline serves as a versatile heterocyclic scaffold in medicinal chemistry, offering enhanced lipophilicity and metabolic stability compared to aromatic analogs. Its benzylic methyl group enables selective functionalization, while the saturated ring facilitates diverse transformations including electrophilic substitution, coupling reactions, and further cyclizations. The compound exhibits good bench stability and is readily purified by standard chromatographic methods, making it a practical building block for API development and target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: