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CS-W001157 4
Total: USD 88.00

6-Bromoimidazo[1,2-a]pyridine-8-carboxylic acid

  • CAS No. 903129-78-2

  • Cat. No. CS-0041611
  • Purity≥97%
  • MDL No.MFCD08448156

*For research and further manufacturing use only, not for direct human use.

6-Bromoimidazo[1,2-a]pyridine-8-carboxylic acid|CS-0041611

Structure of 903129-78-2

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General Information

  • CAS No. 903129-78-2
  • Cat. No. CS-0041611
  • Purity ≥97%
  • MDL No. MFCD08448156
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅BrN₂O₂
  • Molecular Weight 241.04
  • Synonym(s) 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-8-CARBOXYLIC ACID
  • SMILES OC(=O)C1=CC(Br)=CN2C=CN=C12

Description

6-Bromoimidazo[1,2-a]pyridine-8-carboxylic acid features a fused heterocyclic core with complementary bromo and carboxylic acid functionalities. This combination enables direct coupling in cross-coupling reactions and facilitates derivatization for medicinal chemistry applications. The molecule exhibits robust stability under standard bench conditions and integrates readily into complex molecular architectures.

Application

6-Bromoimidazo[1,2-a]pyridine-8-carboxylic acid serves as a versatile building block for the synthesis of biologically active heterocycles. Its bromo and carboxylic acid functionalities enable direct cross-coupling reactions and derivatization under standard conditions. The molecule exhibits good bench stability and facilitates efficient functionalization in medicinal chemistry campaigns targeting kinase inhibitors and other pharmaceutical scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   54.6
  • LogP   1.795
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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