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CS-W001157 4
Total: USD 88.00

6-Bromoimidazo[1,2-a]pyridine-8-carbonitrile

  • CAS No. 911113-15-0

  • Cat. No. CS-0130083
  • Purity≥95%
  • MDL No.MFCD27932269

*For research and further manufacturing use only, not for direct human use.

6-Bromoimidazo[1,2-a]pyridine-8-carbonitrile|CS-0130083

Structure of 911113-15-0

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General Information

  • CAS No. 911113-15-0
  • Cat. No. CS-0130083
  • Purity ≥95%
  • MDL No. MFCD27932269
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrN₃
  • Molecular Weight 222.04
  • Synonym(s) None
  • SMILES N#CC1=CC(Br)=CN2C1=NC=C2

Description

6-Bromoimidazo[1,2-a]pyridine-8-carbonitrile features a rigid heteroaromatic core with complementary electron-withdrawing nitrile and bromide substituents. This combination enables direct functionalization in cross-coupling reactions and facilitates integration into bioactive scaffolds requiring defined electronic properties. The molecule exhibits high stability under standard reaction conditions.

Application

6-Bromoimidazo[1,2-a]pyridine-8-carbonitrile serves as a versatile building block for constructing bioactive heterocycles, enabling palladium-catalyzed cross-coupling reactions with broad functional group tolerance. The bromo and nitrile groups provide orthogonal handles for sequential derivatization, facilitating the synthesis of complex scaffolds relevant to medicinal chemistry and agrochemical development. Its bench-stable crystalline form simplifies handling and purification in multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

  • TPSA   41.09
  • LogP   1.96848
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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