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1H-Indazole-3-carboxamide

  • CAS No. 90004-04-9

  • Cat. No. CS-0132086
  • Purity≥98%
  • MDL No.MFCD09033803
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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*For research and further manufacturing use only, not for direct human use.

1H-Indazole-3-carboxamide|CS-0132086

Structure of 90004-04-9

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Description

1H-Indazole-3-carboxamide features a rigid, planar heteroaromatic core with a carboxamide group at the 3-position, enabling strong hydrogen bonding and enhanced solubility. This scaffold integrates readily into bioactive molecules, offering favorable pharmacokinetic properties and serving as a key motif in kinase inhibitor design.

Application

1H-Indazole-3-carboxamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through standard amide coupling and electrophilic substitution reactions. Its stability under common reaction conditions and favorable solubility profile facilitate straightforward purification and integration into diverse synthetic sequences. Functions effectively as a key intermediate in the development of kinase inhibitors and other bioactive compounds.

General Information

  • CAS No. 90004-04-9
  • Cat. No. CS-0132086
  • Purity ≥98%
  • MDL No. MFCD09033803
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇N₃O
  • Molecular Weight 161.16
  • Synonym(s) 5,6-Difluoro-1H-indazole-3-carboxamide
  • SMILES O=C(C1=NNC2=C1C=CC=C2)N

Computational Chemistry Data

  • TPSA   71.77
  • LogP   0.6618
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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