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CS-W001157 4
Total: USD 88.00

3,4,5-Trimethoxycinnamic acid

  • CAS No. 90-50-6

  • Cat. No. CS-W012839
  • Purity≥98%
  • MDL No.MFCD00004388

*For research and further manufacturing use only, not for direct human use.

3,4,5-Trimethoxycinnamic acid|CS-W012839

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General Information

  • CAS No. 90-50-6
  • Cat. No. CS-W012839
  • Purity ≥98%
  • MDL No. MFCD00004388
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₄O₅
  • Molecular Weight 238.24
  • Synonym(s) None
  • SMILES COC1=C(OC)C(OC)=CC(/C=C/C(O)=O)=C1

Description

3,4,5-Trimethoxycinnamic acid features a conjugated cinnamic acid core decorated with three methoxy groups at the meta and para positions. This substitution pattern enhances solubility and electron density, enabling efficient integration into photoreactive or bioactive scaffolds. The compound serves as a robust building block for synthetic intermediates in medicinal chemistry and materials science.

Application

3,4,5-Trimethoxycinnamic acid serves as a versatile building block in medicinal chemistry and natural product synthesis, enabling efficient access to bioactive scaffolds through standard coupling reactions. Its three methoxy groups enhance solubility and modulate electronic properties, while the cinnamic acid core facilitates facile derivatization via esterification, amidation, or transition-metal-catalyzed cross-coupling. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for high-throughput screening and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   64.99
  • LogP   1.8102
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   5

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