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Structure of 89976-27-2
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Methyl 4-iodo-3-nitrobenzoate features a sterically accessible aromatic core bearing both electron-deficient nitro and iodine substituents, enabling direct functionalization in cross-coupling reactions. The ester group enhances solubility in organic media while maintaining stability under standard conditions. This compound serves as a key intermediate for synthesizing complex heterocycles and bioactive molecules.
Methyl 4-iodo-3-nitrobenzoate serves as a versatile building block in transition metal-catalyzed cross-coupling reactions, enabling efficient access to substituted aromatic scaffolds. The iodide group facilitates reliable Suzuki, Stille, and Negishi couplings, while the nitro and ester functionalities offer orthogonal reactivity for further functionalization. Its bench-stable crystalline form simplifies handling and purification, making it well-suited for iterative synthesis in medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: