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Structure of 3093-97-8
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6-Fluoroindole-2-carboxylic acid features a fluorinated indole core with a carboxylic acid group at the 2-position, enabling direct incorporation into bioactive scaffolds. The electron-withdrawing fluorine at the 6-position enhances metabolic stability and modulates electronic properties for medicinal chemistry applications. This bench-stable derivative supports efficient synthesis of targeted heterocycles and functionalized peptides.
6-Fluoroindole-2-carboxylic acid serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling direct incorporation of fluorinated indole scaffolds into bioactive molecules. Its carboxylic acid functionality facilitates amide bond formation, esterification, and coupling reactions under standard conditions. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the indole core provides a rigid, planar structure suitable for target engagement in kinase inhibitors and CNS-active compounds. Bench-stable and readily purified by recrystallization, it functions reliably in both small-molecule discovery and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: