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Structure of 899452-26-7
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5-Bromo-2-(difluoromethoxy)pyridine is a fluorinated heterocyclic building block featuring a bromine at the 5-position and a difluoromethoxy group at the 2-position. This combination imparts enhanced metabolic stability and electron-withdrawing character, enabling efficient coupling in palladium-catalyzed cross-coupling reactions. The molecule exhibits good solubility in common organic solvents and maintains stability under standard bench conditions.
5-Bromo-2-(difluoromethoxy)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its stable bromo group and compatible difluoromethoxy functionality. The molecule exhibits excellent bench stability and facilitates the construction of complex heterocyclic scaffolds relevant to pharmaceutical development. Its orthogonal reactivity profile supports selective derivatization in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: