Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-2,3-dimethoxypyrazine

  • CAS No. 89466-19-3

  • Cat. No. CS-W006695
  • Purity≥96%
  • MDL No.MFCD18205982

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2,3-dimethoxypyrazine|CS-W006695

Structure of 89466-19-3

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 89466-19-3
  • Cat. No. CS-W006695
  • Purity ≥96%
  • MDL No. MFCD18205982
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂O₂
  • Molecular Weight 219.04
  • Synonym(s) 2-Brom-5,6-dimethoxy-pyrazin
  • SMILES BrC1=CN=C(C(=N1)OC)OC

Description

5-Bromo-2,3-dimethoxypyrazine is a heterocyclic building block featuring a pyrazine core substituted with bromine and two methoxy groups. This configuration imparts enhanced stability and directs regioselective coupling in cross-coupling reactions. The electron-deficient ring facilitates palladium-catalyzed transformations, enabling efficient integration into complex molecular architectures.

Application

5-Bromo-2,3-dimethoxypyrazine serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its stable bromine substituent. The dimethoxy groups enhance solubility and provide orthogonal functional handles for further derivatization. Its bench-stable nature and compatibility with standard reaction conditions make it ideal for medicinal chemistry campaigns and API intermediate development.

Synthesis

  • Route1

    References

    • WO2009/20642 A1, ; Page/Page column 73-74 ; WO 2009/020642 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.24
  • LogP   1.2563
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-2,3-dimethoxypyrazine sigma5-Bromo-2,3-dimethoxypyrazine manufacturer5-Bromo-2,3-dimethoxypyrazine price5-Bromo-2,3-dimethoxypyrazine structure5-Bromo-2,3-dimethoxypyrazine SDSbuy 5-Bromo-2,3-dimethoxypyrazine5-Bromo-2,3-dimethoxypyrazine supplier5-Bromo-2,3-dimethoxypyrazine uses5-Bromo-2,3-dimethoxypyrazine molecular weightprice of 5-Bromo-2,3-dimethoxypyrazine5-Bromo-2,3-dimethoxypyrazine chemical name formula of 5-Bromo-2,3-dimethoxypyrazine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label