Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4-Iodo-2-methoxybenzoic acid

  • CAS No. 89942-34-7

  • Cat. No. CS-0099430
  • Purity≥95%
  • MDL No.MFCD07780726

*For research and further manufacturing use only, not for direct human use.

4-Iodo-2-methoxybenzoic acid|CS-0099430

Structure of 89942-34-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 89942-34-7
  • Cat. No. CS-0099430
  • Purity ≥95%
  • MDL No. MFCD07780726
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇IO₃
  • Molecular Weight 278.04
  • Synonym(s) None
  • SMILES O=C(O)C1=CC=C(I)C=C1OC

Description

4-Iodo-2-methoxybenzoic acid features a strategically positioned iodine atom and methoxy group on the aromatic ring, enabling efficient coupling reactions in late-stage functionalization. The carboxylic acid moiety provides a robust handle for derivatization, while the electron-donating methoxy group enhances reactivity in transition-metal-catalyzed transformations. This compound exhibits stability under standard conditions and compatibility with diverse reaction environments.

Application

4-Iodo-2-methoxybenzoic acid serves as a versatile building block for Suzuki-Miyaura and Negishi coupling reactions, enabling efficient construction of biaryl scaffolds. The iodine handle offers high reactivity under standard palladium catalysis, while the methoxy and carboxylic acid groups provide orthogonal functionality for further derivatization. Bench-stable and readily purified by recrystallization, it functions effectively in both medicinal chemistry and materials synthesis workflows.

Synthesis

  • Route1

    References

    • Wyeth Patent: US2003/55047 A1, 2003 ; US 20030055047 A1
  • Route2

    References

    • Kobayashi,S.; Kuraishi,C. Chemical and Pharmaceutical Bulletin, 1962 , vol. 10, # 12 p. 1137 - 1141
  • Route3
    • 1-(4-Iodo-2-methoxyphenyl)ethan-1-one|CS-1268775
      90347-64-1
    • ~%
    • In-stock
      4-Iodo-2-methoxybenzoic acid|CS-0099430
      89942-34-7

    References

    • Kobayashi,S.; Kuraishi,C. Chemical and Pharmaceutical Bulletin, 1962 , vol. 10, # 12 p. 1137 - 1141

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.998
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4-Iodo-2-methoxybenzoic acid sigma4-Iodo-2-methoxybenzoic acid manufacturer4-Iodo-2-methoxybenzoic acid price4-Iodo-2-methoxybenzoic acid structure4-Iodo-2-methoxybenzoic acid SDSbuy 4-Iodo-2-methoxybenzoic acid4-Iodo-2-methoxybenzoic acid supplier4-Iodo-2-methoxybenzoic acid uses4-Iodo-2-methoxybenzoic acid molecular weightprice of 4-Iodo-2-methoxybenzoic acid4-Iodo-2-methoxybenzoic acid chemical name formula of 4-Iodo-2-methoxybenzoic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label