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CS-W001157 4
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Thietan-3-ol

  • CAS No. 10304-16-2

  • Cat. No. CS-0045447
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Thietan-3-ol|CS-0045447

Structure of 10304-16-2

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General Information

  • CAS No. 10304-16-2
  • Cat. No. CS-0045447
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₆OS
  • Molecular Weight 90.14
  • Synonym(s) 3-Thietanol
  • SMILES OC1CSC1

Description

Thietan-3-ol features a strained five-membered ring with a hydroxyl group at the 3-position, delivering enhanced reactivity for synthetic transformations. The molecule exhibits bench-stable handling under standard conditions and integrates readily into complex heterocyclic architectures.

Application

Thietan-3-ol serves as a valuable synthetic building block for strained heterocycles, enabling controlled ring-opening reactions and functionalization at the 3-position. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient access to sulfur-containing scaffolds relevant in medicinal chemistry. Functions as a versatile intermediate in the construction of bioactive heterocyclic frameworks.

Synthesis

  • Route1

    References

    • Devan, Naduthambi; Sridhar, Perali Ramu; Prabhu, Kandikere Ramaiah; Chandrasekaran, Srinivasan Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9417 - 9420
  • Route2
    • null|null
      106-89-8
    • ~90%
    • In-stock
      Thietan-3-ol|CS-0045447
      10304-16-2

    References

    • Devan, Naduthambi; Sridhar, Perali Ramu; Prabhu, Kandikere Ramaiah; Chandrasekaran, Srinivasan Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9417 - 9420
  • Route3
    • 2-(Chloromethyl)thiirane|CS-0232950
      3221-15-6
    • ~%
    • In-stock
      Thietan-3-ol|CS-0045447
      10304-16-2
    • null|null
      1418193-25-5

    References

    • SYNGENTA PARTICIPATIONS AG; CASSAYRE, Jérôme Yves; GODINEAU, Edouard; BOUSSEMGHOUNE, Mohamed Abdelouahab; SMITS, Helmars Patent: WO2013/7582 A2, 2013 ; Location in patent: Page/Page column 38; 39 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   0.0941
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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