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CS-W001157 4
Total: USD 88.00

Methyl 2-hydroxy-4-iodobenzoate

  • CAS No. 18179-39-0

  • Cat. No. CS-W007286
  • Purity≥96%
  • MDL No.MFCD06797864

*For research and further manufacturing use only, not for direct human use.

Methyl 2-hydroxy-4-iodobenzoate|CS-W007286

Structure of 18179-39-0

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General Information

  • CAS No. 18179-39-0
  • Cat. No. CS-W007286
  • Purity ≥96%
  • MDL No. MFCD06797864
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇IO₃
  • Molecular Weight 278.04
  • Synonym(s) Methyl 4-iodosalicylate
  • SMILES O=C(OC)C1=CC=C(I)C=C1O

Description

Methyl 2-hydroxy-4-iodobenzoate features a strategically positioned hydroxyl group and iodine substituent on the aromatic ring, enabling direct functionalization via cross-coupling or derivatization. The ester moiety enhances solubility in organic solvents while maintaining stability under standard bench conditions. This compound serves as a key intermediate for synthesizing bioactive molecules and advanced pharmaceutical scaffolds.

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      2-Hydroxy-4-iodobenzoic acid|CS-0103689
      16870-28-3
    • ~51%
    • In-stock
      Methyl 2-hydroxy-4-iodobenzoate|CS-W007286
      18179-39-0

    References

    • BASF SE; BASF (CHINA) COMPANY LIMITED; MAURER, Stefan; MÜLLER, Ulrich; SWAMINATHAN, Vijay Narayanan; HINDALEKAR, Shrirang Bhikaji; PANDYA, Amal Patent: WO2014/45135 A1, 2014 ; Location in patent: Page/Page column 16-17 ;
  • Route2
    • In-stock
      2-Hydroxy-4-iodobenzoic acid|CS-0103689
      16870-28-3
    • null|null
      18107-18-1
    • ~%
    • In-stock
      Methyl 2-hydroxy-4-iodobenzoate|CS-W007286
      18179-39-0

    References

    • US2008/194668 A1, ; Page/Page column 7 ;
  • Route3

    References

    • Park, Ju-Young; Kim, Seung-Woo; Park, Ho-Joon; Im, Weon Bin; Lee, Ja-Kyeong; Yoon, Sung-Hwa Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 12 p. 3860 - 3863

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.7834
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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