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Structure of 89942-34-7
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4-Iodo-2-methoxybenzoic acid features a strategically positioned iodine atom and methoxy group on the aromatic ring, enabling efficient coupling reactions in late-stage functionalization. The carboxylic acid moiety provides a robust handle for derivatization, while the electron-donating methoxy group enhances reactivity in transition-metal-catalyzed transformations. This compound exhibits stability under standard conditions and compatibility with diverse reaction environments.
4-Iodo-2-methoxybenzoic acid serves as a versatile building block for Suzuki-Miyaura and Negishi coupling reactions, enabling efficient construction of biaryl scaffolds. The iodine handle offers high reactivity under standard palladium catalysis, while the methoxy and carboxylic acid groups provide orthogonal functionality for further derivatization. Bench-stable and readily purified by recrystallization, it functions effectively in both medicinal chemistry and materials synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: