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CS-W001157 4
Total: USD 88.00

Diethyl(3-pyridyl)borane

  • CAS No. 89878-14-8

  • Cat. No. CS-B0611
  • Purity≥97%
  • MDL No.MFCD00012348

*For research and further manufacturing use only, not for direct human use.

Diethyl(3-pyridyl)borane|CS-B0611

Structure of 89878-14-8

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General Information

  • CAS No. 89878-14-8
  • Cat. No. CS-B0611
  • Purity ≥97%
  • MDL No. MFCD00012348
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄BN
  • Molecular Weight 147.03
  • Synonym(s) Diethyl-(pyridin-3-yl)-borane
  • SMILES CCB(C1=CC=CN=C1)CC

Description

Crotonoyl coenzyme A (2-Butenoyl coenzyme A) may be used as a substrate of enzymes such as Plasmodium falciparum enoyl-ACP reductase and other enoyl-CoA reductases. Crotonoyl CoA may be used as a substrate analogue for kinetic studies on -hydroxyacyl-acyl carrier protein (ACP) dehydratase (FabZ).

Application

Diethyl(3-pyridyl)borane serves as a versatile boron reagent for palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its pyridyl moiety provides enhanced solubility and stability compared to simpler alkylboranes, while the diethyl group facilitates clean transmetalation. The compound exhibits excellent functional group tolerance and is particularly useful in constructing heteroaromatic scaffolds common in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • In-stock
      3-Bromopyridine|CS-0008362
      626-55-1
    • null|null
      7397-46-8
    • ~75%
    • In-stock
      Diethyl(3-pyridyl)borane|CS-B0611
      89878-14-8

    References

    • Cai, Weiling; Brown Ripin, David H. Synlett, 2002 , # 2 p. 273 - 274
  • Route2
    • null|null
      1120-87-2
    • ~%
    • In-stock
      Diethyl(3-pyridyl)borane|CS-B0611
      89878-14-8
    • null|null
      93830-58-1

    References

    • US5502065 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   1.8232
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   3

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