4-Chloro-2-fluoro-1-nitrobenzene

Name: 4-Chloro-2-fluoro-1-nitrobenzene
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 700-37-8
Cat. No. CS-W002202
Purity≥98%
MDL No.MFCD00042211

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Chloro-2-fluoro-1-nitrobenzene|CS-W002202

Structure of 700-37-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 700-37-8
Cat. No. CS-W002202
Purity ≥98%
MDL No. MFCD00042211
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₃ClFNO₂
Molecular Weight 175.55
Synonym(s) 1-CHLORO-3-FLUORO-4-NITROBENZENE
SMILES Clc1ccc(c(c1)F)[N+](=O)[O-]

Description

4-Chloro-2-fluoro-1-nitrobenzene features a trifunctional aromatic core with complementary reactivity for downstream synthesis. The electron-deficient ring facilitates nucleophilic substitution, while the ortho-fluoro and para-chloro groups enable selective functionalization. This bench-stable compound integrates efficiently into complex molecular architectures under standard conditions.

Application

4-Chloro-2-fluoro-1-nitrobenzene serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted heterocycles and pharmaceutical intermediates. Its orthogonal halogenation pattern facilitates selective metal-catalyzed cross-coupling reactions, while the nitro group supports sequential transformations including reduction to aniline derivatives. The compound exhibits excellent bench stability and is compatible with standard purification protocols, making it well-suited for scalable synthesis and process development workflows.

Synthesis

Route1
- 611-06-3
- ~0%
- In-stock
  
  2106-50-5
- In-stock
  
  446-35-5
- In-stock
  
  700-37-8
References
- Sasson, Yoel; Negussie, Samuel; Royz, Michael; Mushkin, Noam Chemical Communications, 1996 , # 3 p. 297 - 298
Route2
- 611-06-3
- ~13%
- In-stock
  
  446-35-5
- In-stock
  
  700-37-8
References
- US2004/24238 A1, ; Page 5 ;
Route3
- 611-06-3
- ~7%
- In-stock
  
  700-37-8
References
- Laurain, Nathalie; Zard, Samir Patent: US2004/24238 A1, 2004 ; Location in patent: Page 5 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 43.14
LogP 2.3873
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Nitro compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

4-Chloro-2-fluoro-1-nitrobenzene sigma4-Chloro-2-fluoro-1-nitrobenzene manufacturer4-Chloro-2-fluoro-1-nitrobenzene price4-Chloro-2-fluoro-1-nitrobenzene structure4-Chloro-2-fluoro-1-nitrobenzene SDSbuy 4-Chloro-2-fluoro-1-nitrobenzene4-Chloro-2-fluoro-1-nitrobenzene supplier4-Chloro-2-fluoro-1-nitrobenzene uses4-Chloro-2-fluoro-1-nitrobenzene molecular weightprice of 4-Chloro-2-fluoro-1-nitrobenzene4-Chloro-2-fluoro-1-nitrobenzene chemical name formula of 4-Chloro-2-fluoro-1-nitrobenzene

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Chloro-2-fluoro-1-nitrobenzene

CAS No. 700-37-8

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words