Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5,6-Dichloropyridazin-4-amine

  • CAS No. 89180-50-7

  • Cat. No. CS-0060122
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

5,6-Dichloropyridazin-4-amine|CS-0060122

Structure of 89180-50-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 89180-50-7
  • Cat. No. CS-0060122
  • Purity ≥96%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃Cl₂N₃
  • Molecular Weight 163.99
  • Synonym(s) 5-Amino-3,4-dichloropyridazine
  • SMILES C1=C(C(=C(Cl)N=N1)Cl)N

Description

5,6-Dichloropyridazin-4-amine is a chlorinated pyridazine derivative featuring two chlorine substituents at the 5- and 6-positions, enhancing its electron-deficient character. This configuration facilitates nucleophilic substitution reactions and enables integration into bioactive scaffolds. The compound serves as a key intermediate in medicinal chemistry for constructing heterocyclic libraries targeting kinase inhibitors and antiviral agents. Its bench-stable nature supports reliable handling under standard conditions.

Application

5,6-Dichloropyridazin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic substitution and cross-coupling reactions. Its dual chlorine substituents provide orthogonal reactivity for sequential functionalization, facilitating the synthesis of complex pyridazinone derivatives and drug-like molecules. The compound exhibits good bench stability and compatibility with standard purification protocols, making it well-suited for iterative synthesis campaigns in API development.

Synthesis

  • Route1

    References

    • Journal of Heterocyclic Chemistry, , vol. 32, # 5 p. 1423 - 1428
  • Route2
    • null|null
      105398-92-3
    • ~86%
    • In-stock
      5,6-Dichloropyridazin-4-amine|CS-0060122
      89180-50-7

    References

    • Merslavic, Mario; Stanovnik, Branko; Tisler, Miha Monatshefte fuer Chemie, 1985 , vol. 116, p. 1447 - 1458
  • Route3

    References

    • Chemical and Pharmaceutical Bulletin, , vol. 6, p. 641,644

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   1.3656
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5,6-Dichloropyridazin-4-amine sigma5,6-Dichloropyridazin-4-amine manufacturer5,6-Dichloropyridazin-4-amine price5,6-Dichloropyridazin-4-amine structure5,6-Dichloropyridazin-4-amine SDSbuy 5,6-Dichloropyridazin-4-amine5,6-Dichloropyridazin-4-amine supplier5,6-Dichloropyridazin-4-amine uses5,6-Dichloropyridazin-4-amine molecular weightprice of 5,6-Dichloropyridazin-4-amine5,6-Dichloropyridazin-4-amine chemical name formula of 5,6-Dichloropyridazin-4-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label