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CS-W001157 4
Total: USD 88.00

3-Bromo-6-chloro-2-fluoropyridine

  • CAS No. 885952-18-1

  • Cat. No. CS-W006313
  • Purity≥95%
  • MDL No.MFCD06798230

*For research and further manufacturing use only, not for direct human use.

3-Bromo-6-chloro-2-fluoropyridine|CS-W006313

Structure of 885952-18-1

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General Information

  • CAS No. 885952-18-1
  • Cat. No. CS-W006313
  • Purity ≥95%
  • MDL No. MFCD06798230
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₂BrClFN
  • Molecular Weight None
  • Synonym(s) 2-Chloro-5-bromo-6-fluoropyridine
  • SMILES FC1=NC(Cl)=CC=C1Br

Description

3-Bromo-6-chloro-2-fluoropyridine is a halogenated pyridine derivative featuring strategically positioned bromo, chloro, and fluoro substituents. This combination imparts enhanced electrophilic reactivity and metabolic stability, making it valuable for constructing complex heterocyclic architectures in medicinal chemistry and agrochemical synthesis under standard conditions.

Application

3-Bromo-6-chloro-2-fluoropyridine serves as a versatile trifunctional pyridine building block for cross-coupling and nucleophilic substitution reactions. Its orthogonal halogen reactivity enables sequential functionalization in medicinal chemistry and agrochemical synthesis, while its bench-stable nature facilitates handling and purification. The compound functions effectively in Pd-catalyzed couplings, allowing access to complex heterocyclic scaffolds with precise substitution patterns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.6366
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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